Safety Data Sheet

Product Name: Recombinant Zebrafish VEGF 165

Reviewed on: 27 February 2012

   Exposure controls Appropriate engineering controls: Use only with adequate ventilation. Use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits. The engineering controls also need to keep gas, vapor or dust concentrations below any lower explosive limits. Use explosion-proof ventilation equipment.

Individual protection measures Hygiene measures: Wash hands, forearms and face thoroughly after handling chemical products,

before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location.

Eye/face protection: Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is

necessary to avoid exposure to liquid splashes, mists, gases or dusts.

Skin protection Hand protection: Chemical-resistant, impervious gloves complying with an approved standard should be worn at all

times when handling chemical products if a risk assessment indicates this is necessary.

Body protection: Personal protective equipment for the body should be selected based on the task being performed and the risks

involved and should be approved by a specialist before handling this product.

Other skin protection: Appropriate footwear and any additional skin protection measures should be selected based on the task being

performed and the risks involved and should be approved by a specialist before handling this product.

Respiratory protection: Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk

assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator.

Environmental exposure controls: Emissions from ventilation or work process equipment should be checked to ensure they comply

with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

9. Physical and Chemical Properties:

     Appearance: Colorless Liquid                                           Upper/lower flammability or explosive limits: Not available.

     Odor: Not available.                                                           Vapor pressure: 73 mmHg at 20o C.

     Odor threshold:                                                                 Vapor density : Not available

     pH: 2.0 ± 0.3                                                                       Relative density: 0.786 g/mL at 20o C.

     Melting point/freezing point: Undetermined.                   Solubility in/Miscibility with Water: Soluble.

     Boiling point/Boiling range: 82.0o C (180o F)                 Partition coefficient: noctanol/water: Not available.

     Flash point: 5° C                                                               Auto igniting: Product is not self igniting.

     Evaporation rate: Not available                                         Decomposition temperature: Not available

   Flammability (solid, gas): Not available.                         Viscosity: Undetermined.

10. Stability and Reactivity:

   Reactivity: No specific test data related to reactivity available for this product or its ingredients.

   Chemical Stability: Stable under normal ambient storage and handling temperatures.

   Possibility of hazardous reactions: Under normal conditions of storage and use, hazardous reactions will not occur.

   Conditions to be avoided: Avoid all possible sources of ignition (heat, spark, flame and direct sunlight).

   Incompatible materials to be avoided: Oxidizing or reducing materials, acids and bases, sulfites, perchlorates, alcohols and aluminum.

May attack many plastics, rubbers and coatings.

   Hazardous decomposition products: In case of fire hazardous decomposition products may be produced such as: Hydrogen cyanide

(hydrocyanic acid), carbon dioxide, carbon monoxide, oxides of nitrogen, dense black smoke.

11. Toxicological Information:

   Acute toxicity:

   Skin irritant effect: .Acetonitrile – Mild irritant rabbit